About the Authors

Kevin A Wilkinson

Affiliation Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina, United States of America

Robert J Gorelick

Affiliation AIDS Vaccine Program, SAIC-Frederick, National Cancer Institute-Fredrick, Frederick, Maryland, United States of America

Suzy M Vasa

Affiliation Department of Biomedical Engineering, University of North Carolina, Chapel Hill, North Carolina, United States of America

Nicolas Guex

Affiliation Swiss Institute of Bioinformatics, Lausanne, Switzerland

Alan Rein

Affiliation HIV Drug Resistance Program, National Cancer Institute-Fredrick, Frederick, Maryland, United States of America

David H Mathews

Affiliation Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, New York, United States of America

Morgan C Giddings

Affiliations Department of Biomedical Engineering, University of North Carolina, Chapel Hill, North Carolina, United States of America , Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, United States of America , Department of Computer Science, University of North Carolina, Chapel Hill, North Carolina, United States of America

Kevin M Weeks

To whom correspondence should be addressed. E-mail: weeks@unc.edu

Affiliation Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina, United States of America

Competing Interests

KAW, SMV, NG, MCG and KMW have applied for a patent related to some of the technology described in this work.

Author Contributions

KAW, RJG, AR, and KMW conceived and designed the experiments. KAW and RJG performed the experiments. KAW, SMV, and KMW analyzed the data. RJG, SMV, NG, DHM, and MCG contributed materials and analysis tools. KAW and KMW wrote the paper with contributions from RJG, SMV, NG, AR, DHM, and MCG.