About the Authors

Linda J Porrino

Affiliation Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America

James B Daunais

Affiliation Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America

Gary A Rogers

Affiliation Cortex Pharmaceuticals, Irvine, California, United States of America

Robert E Hampson

Affiliation Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America

Sam A Deadwyler

To whom correspondence should be addressed. E-mail: sdeadwyl@wfubmc.edu

Affiliation Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America

Competing Interests

Portions of the research were supported by Cortex Pharmaceuticals in that Cortex donated the drug CX717, and GAR, an employee of Cortex, contributed expertise in drug formulation, experimental design, and manuscript review. This collaboration provided access to certain technologies and scientific expertise for basic research in the study of the effects of sleep deprivation on cognitive performance.

Author Contributions

LJP, JBD, GAR, REH, and SAD conceived and designed the experiments. LJP, JBD, REH, and SAD performed the experiments. LJP, JBD, GAR, REH, and SAD analyzed the data. GAR contributed reagents/materials/analysis tools. LJP, JBD, GAR, REH, and SAD wrote the paper.