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Revising Your Manuscript

Submission Instructions

If you are submitting a revised manuscript, upload your revised submission to the submission system and include the following items:

  • Response to reviewers: Address the specific points made by each reviewer. Include your responses to all the reviewers’ and editors’ comments and list the changes you have made to the manuscript. Remember, if you choose to publish the peer review history of your manuscript, your response to reviewers will appear online alongside the final article. Upload this document as a “Response to reviewers” file.

  • Revised manuscript (marked-up copy): Include a marked-up copy of your manuscript file showing the changes you have made since the original submission. The best way to show these changes is the “Track Changes” option in Microsoft Word. Upload this as a "Revised Article with Changes Highlighted” file.

  • Revised manuscript (clean copy): Upload a clean copy of your revised manuscript that does not show your changes. Upload this as your “Manuscript” file.

Figures and supporting information files from your original submission will automatically transfer to your revised submission unless you choose to update and replace them. 

Request an Extension

Need more time to prepare your revision? Email digitalhealth@plos.org

Updating a preprint

If you choose to post your manuscript to a preprint server before or during submission to PLOS, you can update or revise your preprint up until the point of acceptance for publication. Please consult the preprint server for specific instructions.