After this article [1] was published, concerns were raised regarding results presented in Figs 2, 4, 5, and S2.

Specifically:

• The following results appear similar when color levels are adjusted:
  1. ◦ Fig 2B,
     • LPL Nb5 Nb-EGFP CL panel, LPL Nb5 Nb-EGFP -Dox panel, and LPL Nb9 Nb-EGFP CL panel.
     • EGFP EGFP CL panel and EGFP EGFP -Dox panel.
     • GSN Nb11 Nb-EGFP CL panel and GSN Nb13 Nb-EGFP CL panel.
  2. ◦ Fig 2C LPL Nb5 Actin blot and Figure 2C CapG Nb4 Actin blot.
• The following results appear similar despite representing different experimental conditions:
  1. ◦ Fig 4D Pro-MMP9 MMP9 EGFP CapG Nb4 panel and Figure 4D Pro-MMP9 MMP9 GSN Nb11 GSN Nb13 panel when flipped horizontally.
  2. ◦ Fig S2A lanes 3 and 6.
  3. ◦ Fig S2B lanes 1–2 and S2B Figure lanes 5–6 when flipped horizontally.
• There appear to be vertical or horizontal discontinuities in the following panels:
  1. ◦ Fig 2B G.S.N. Nb11 GSN +Dox
  2. ◦ Fig 2B G.S.N. Nb13 GSN +Dox
  3. ◦ Fig 4C between lanes 1 and 2, and between lanes 4 and 5.
  4. ◦ Fig 4E between lanes 2 and 3.
  5. ◦ Fig 5B G.S.N. Nb11 Phospho-LPL, L.P.L. Nb5 Phospho-LPL, L.P.L. Nb5 LPL, LPL Nb9 Phospho-LPL and L.P.L. Nb9 LPL
  6. ◦ Fig S2A between lanes 4 and 5.

The authors did not respond to editorial requests for a response and underlying data. In light of the above unresolved concerns that question the integrity and reliability of the reported results and conclusions, the PLOS One Editors retract this article.

All authors either did not respond directly or could not be reached.