Figures
There are a number of errors in the caption for Fig 3, “Comparison of different transgenic mice reveals stimulus-intensity specific responses to noxious thermal stimuli.” Please see the complete, correct Fig 3 caption here.
Behavioural responses of different Nav1.7 tissue-specific knockouts to the Hargreaves test applied to the hindpaw. (a) Nav1.7Nav1.8 mice (blue columns, n = 14), Nav1.7Advill mice (red column, n = 7) and Nav1.7Wnt1 mice (green column, n = 12) all show a behavioural deficit in response to the Hargreaves test at a heat ramp of 0.6°C.s−1 in comparison to littermate mice (white columns, n = 27), however (b) only Nav1.7Advill and Nav1.7Wnt1 mice show a behavioural deficit in response to the Hargreaves test at a heat ramp of 2.0°C.s−1. (c) Nav1.8KO mice (light blue column, n = 6) and Nav1.9KO mice (turquoise column, n = 10) but not Nav1.3KO mice (orange column, n = 6) show a significantly increased withdrawal latency to the Hargreaves test at a heat ramp of 0.6°C.s−1 in comparison to littermate mice (white columns, n = 18), however this significant increase is lost the when the Hargreaves test is conducted using a heat ramp of 2.0°C.s−1. Data analysed by two-way analysis of variance followed by a Bonferroni post-hoc test. Results are presented as mean ± S.E.M. * P<0.05 and *** P<0.001 (individual points).
Reference
- 1. Minett MS, Eijkelkamp N, Wood JN (2014) Significant Determinants of Mouse Pain Behaviour. PLOS ONE 9(8): e104458. https://doi.org/10.1371/journal.pone.0104458 pmid:25101983
Citation: Minett MS, Eijkelkamp N, Wood JN (2021) Correction: Significant Determinants of Mouse Pain Behaviour. PLoS ONE 16(1): e0245813. https://doi.org/10.1371/journal.pone.0245813
Published: January 15, 2021
Copyright: © 2021 Minett et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.