Tokiinshi, a traditional Japanese medicine (Kampo), suppresses Panton-Valentine leukocidin production in the methicillin-resistant Staphylococcus aureus USA300 clone

Yuka Maezawa; Hidemasa Nakaminami; Shunsuke Takadama; Minami Hayashi; Takeaki Wajima; Keisuke Nakase; Tetsuya Yamada; Hideaki Ikoshi; Norihisa Noguchi

doi:10.1371/journal.pone.0214470

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Open Access

Peer-reviewed

Research Article

Tokiinshi, a traditional Japanese medicine (Kampo), suppresses Panton-Valentine leukocidin production in the methicillin-resistant Staphylococcus aureus USA300 clone

Yuka Maezawa,

Roles Data curation, Formal analysis, Investigation, Visualization, Writing – original draft

Affiliation Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan
⨯
Hidemasa Nakaminami ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: nakami@toyaku.ac.jp

Affiliation Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan

http://orcid.org/0000-0003-2889-8257

⨯
Shunsuke Takadama,

Roles Investigation

Affiliation Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan
⨯
Minami Hayashi,

Roles Investigation

Affiliation Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan
⨯
Takeaki Wajima,

Roles Data curation, Methodology, Supervision

Affiliation Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan

http://orcid.org/0000-0001-9506-707X

⨯
Keisuke Nakase,

Roles Resources, Supervision

Affiliation Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan
⨯
Tetsuya Yamada,

Roles Resources, Supervision

Affiliation Department of Traditional Chinese Medicine, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan
⨯
Hideaki Ikoshi,

Roles Resources, Supervision

Affiliation Department of Traditional Chinese Medicine, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan
⨯
Norihisa Noguchi

Roles Funding acquisition, Supervision, Validation, Writing – review & editing

Affiliation Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan
⨯

Tokiinshi, a traditional Japanese medicine (Kampo), suppresses Panton-Valentine leukocidin production in the methicillin-resistant Staphylococcus aureus USA300 clone

Yuka Maezawa,
Hidemasa Nakaminami,
Shunsuke Takadama,
Minami Hayashi,
Takeaki Wajima,
Keisuke Nakase,
Tetsuya Yamada,
Hideaki Ikoshi,
Norihisa Noguchi

Published: March 28, 2019
https://doi.org/10.1371/journal.pone.0214470

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