Downregulation of PIK3CA via antibody-esiRNA-complexes suppresses human xenograft tumor growth

• Nicole Bäumer,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Validation, Writing – original draft

  Affiliation Department of Medicine A, Hematology/Oncology, University of Muenster, Muenster, Germany

  http://orcid.org/0000-0002-7530-467X

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• Jan Rehkämper,

  Roles Investigation, Methodology

  Affiliation Gerhard-Domagk Institute for Pathology, University of Muenster, Muenster, Germany

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• Neele Appel,

  Roles Investigation

  Affiliation Department of Medicine A, Hematology/Oncology, University of Muenster, Muenster, Germany

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• Lisa Terheyden,

  Roles Investigation, Methodology

  Affiliation Department of Medicine A, Hematology/Oncology, University of Muenster, Muenster, Germany

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• Wolfgang Hartmann,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – review & editing

  Affiliation Gerhard-Domagk Institute for Pathology, University of Muenster, Muenster, Germany

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• Eva Wardelmann,

  Roles Conceptualization, Supervision

  Affiliation Gerhard-Domagk Institute for Pathology, University of Muenster, Muenster, Germany

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• Frank Buchholz,

  Roles Conceptualization, Data curation, Supervision, Writing – review & editing

  Affiliations Universitäts KrebsCentrum (UCC), Medical Systems Biology, Medical Faculty, Technische Universität Dresden, Dresden, Germany, German Cancer Research Center (DKFZ), Heidelberg and German Cancer Consortium (DKTK) Partner Site, Dresden, Germany, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany, National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

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• Carsten Müller-Tidow,

  Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

  Affiliations Department of Medicine A, Hematology/Oncology, University of Muenster, Muenster, Germany, Department of Medicine V, University of Heidelberg, Heidelberg, Germany

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• Wolfgang E. Berdel,

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Writing – review & editing

  Affiliation Department of Medicine A, Hematology/Oncology, University of Muenster, Muenster, Germany

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• Sebastian Bäumer

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft

  * E-mail: baumers@uni-muenster.de

  Affiliation Department of Medicine A, Hematology/Oncology, University of Muenster, Muenster, Germany

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