Atypical E2f functions are critical for pancreas polyploidization

Ramadhan B. Matondo; Eva Moreno; Mathilda J. M. Toussaint; Peter C. J. Tooten; Saskia C. van Essen; Elsbeth A. van Liere; Sameh A. Youssef; Laura Bongiovanni; Alain de Bruin

doi:10.1371/journal.pone.0190899

Loading metrics

Open Access

Peer-reviewed

Research Article

Atypical E2f functions are critical for pancreas polyploidization

Ramadhan B. Matondo,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands

http://orcid.org/0000-0001-5529-100X

⨯
Eva Moreno,

Roles Investigation

Affiliation Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
⨯
Mathilda J. M. Toussaint,

Roles Investigation

Affiliation Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
⨯
Peter C. J. Tooten,

Roles Investigation

Affiliation Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
⨯
Saskia C. van Essen,

Roles Investigation

Affiliation Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
⨯
Elsbeth A. van Liere,

Roles Investigation

Affiliation Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
⨯
Sameh A. Youssef,

Roles Formal analysis, Investigation

Affiliation Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
⨯
Laura Bongiovanni,

Roles Formal analysis, Investigation

Affiliation Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
⨯
Alain de Bruin

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: A.deBruin@uu.nl

Affiliations Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands, Department of Paediatrics, Division of Molecular Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
⨯

Atypical E2f functions are critical for pancreas polyploidization

Ramadhan B. Matondo,
Eva Moreno,
Mathilda J. M. Toussaint,
Peter C. J. Tooten,
Saskia C. van Essen,
Elsbeth A. van Liere,
Sameh A. Youssef,
Laura Bongiovanni,
Alain de Bruin

Published: January 12, 2018
https://doi.org/10.1371/journal.pone.0190899

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Polyploidy
Is the Subject Area "Polyploidy" applicable to this article?

Thanks for your feedback.
Pancreas
Is the Subject Area "Pancreas" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Genetically modified animals
Is the Subject Area "Genetically modified animals" applicable to this article?

Thanks for your feedback.
Insulin
Is the Subject Area "Insulin" applicable to this article?

Thanks for your feedback.
Glucose
Is the Subject Area "Glucose" applicable to this article?

Thanks for your feedback.
Cell staining
Is the Subject Area "Cell staining" applicable to this article?

Thanks for your feedback.
Nuclear staining
Is the Subject Area "Nuclear staining" applicable to this article?

Thanks for your feedback.