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Open Access
Peer-reviewed
Research Article
Deficient Mechanical Activation of Anabolic Transcripts and Post-Traumatic Cartilage Degeneration in Matrilin-1 Knockout Mice
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Yupeng Chen ,
* E-mail: Yupeng_Chen@Brown.edu (YC); Qian_Chen@Brown.edu (QC)
Affiliations Bone and Joint Research Center, The First Affiliated Hospital and Frontier Institute of Science and Technology, Xi’an JiaoTong University, Xi’an, 710061, China, Department of Orthopaedics, Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, RI, 02903, United States of America
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Jack Cossman,
Affiliation Department of Orthopaedics, Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, RI, 02903, United States of America
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Chathuraka T. Jayasuriya,
Affiliation Department of Orthopaedics, Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, RI, 02903, United States of America
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Xin Li,
Affiliation Department of Orthopaedics, Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, RI, 02903, United States of America
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Yingjie Guan,
Affiliation Department of Orthopaedics, Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, RI, 02903, United States of America
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Vera Fonseca,
Affiliation Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, RI, 02912, United States of America
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Kun Yang,
Affiliation Department of Orthopaedics, Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, RI, 02903, United States of America
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Cherie Charbonneau,
Affiliation Department of Orthopaedics, Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, RI, 02903, United States of America
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Hongchuan Yu,
Affiliations Bone and Joint Research Center, The First Affiliated Hospital and Frontier Institute of Science and Technology, Xi’an JiaoTong University, Xi’an, 710061, China, Department of Orthopaedics, Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, RI, 02903, United States of America
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Katsuaki Kanbe,
Affiliation Department of Orthopaedic Surgery, Tokyo Women’s Medical University, Medical Center East, Tokyo, Japan
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Peter Ma,
Affiliation Department of Biologic and Materials Science, University of Michigan, Ann Arbor, Michigan, 48109, United States of America
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Eric Darling,
Affiliations Department of Orthopaedics, Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, RI, 02903, United States of America, Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, RI, 02912, United States of America, Center for Biomedical Engineering, Brown University, Providence, RI, 02912, United States of America
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Qian Chen
* E-mail: Yupeng_Chen@Brown.edu (YC); Qian_Chen@Brown.edu (QC)
Affiliations Bone and Joint Research Center, The First Affiliated Hospital and Frontier Institute of Science and Technology, Xi’an JiaoTong University, Xi’an, 710061, China, Department of Orthopaedics, Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, RI, 02903, United States of America
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Deficient Mechanical Activation of Anabolic Transcripts and Post-Traumatic Cartilage Degeneration in Matrilin-1 Knockout Mice
- Yupeng Chen,
- Jack Cossman,
- Chathuraka T. Jayasuriya,
- Xin Li,
- Yingjie Guan,
- Vera Fonseca,
- Kun Yang,
- Cherie Charbonneau,
- Hongchuan Yu,
- Katsuaki Kanbe
- Published: June 7, 2016
- https://doi.org/10.1371/journal.pone.0156676