Hierarchy Low CD4+/CD8+ T-Cell Counts and IFN-γ Responses in HIV-1+ Individuals Correlate with Active TB and/or M.tb Co-Infection

Lingyun Shao; Xinyun Zhang; Yan Gao; Yunya Xu; Shu Zhang; Shenglei Yu; Xinhua Weng; Hongbo Shen; Zheng W. Chen; Weimin Jiang; Wenhong Zhang

doi:10.1371/journal.pone.0150941

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Peer-reviewed

Research Article

Hierarchy Low CD4+/CD8+ T-Cell Counts and IFN-γ Responses in HIV-1+ Individuals Correlate with Active TB and/or M.tb Co-Infection

Lingyun Shao ,

Contributed equally to this work with: Lingyun Shao, Xinyun Zhang

Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China
⨯
Xinyun Zhang ,

Contributed equally to this work with: Lingyun Shao, Xinyun Zhang

Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China
⨯
Yan Gao,

Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China
⨯
Yunya Xu,

Affiliation Department of Infectious Diseases, Honghe No.1 People’s Hospital, Mengzi, Mengzi County, 661100, China
⨯
Shu Zhang,

Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China
⨯
Shenglei Yu,

Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China
⨯
Xinhua Weng,

Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China
⨯
Hongbo Shen,

Affiliation Chinese Academy of Science and Institute Pasteur of Shanghai, Shanghai, 200040, China
⨯
Zheng W. Chen,

Affiliation Department of Microbiology & Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine, Chicago, Illinois, 60612, United States of America
⨯
Weimin Jiang ,

* E-mail: zhangwenhong@fudan.edu.cn (WZ); jiangweimin2004@163.com (WJ)

Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China
⨯
Wenhong Zhang

* E-mail: zhangwenhong@fudan.edu.cn (WZ); jiangweimin2004@163.com (WJ)

Current address: Key Laboratory of Medical Molecular Virology, Ministry of Education and Health, Shanghai Medical College, and Institutes of Biomedical Science, Fudan University, Shanghai, China

Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China
⨯

Hierarchy Low CD4+/CD8+ T-Cell Counts and IFN-γ Responses in HIV-1+ Individuals Correlate with Active TB and/or M.tb Co-Infection

Lingyun Shao,
Xinyun Zhang,
Yan Gao,
Yunya Xu,
Shu Zhang,
Shenglei Yu,
Xinhua Weng,
Hongbo Shen,
Zheng W. Chen,
Weimin Jiang

Published: March 9, 2016
https://doi.org/10.1371/journal.pone.0150941

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