FTY720 Treatment in the Convalescence Period Improves Functional Recovery and Reduces Reactive Astrogliosis in Photothrombotic Stroke

Robert Brunkhorst; Nathalie Kanaan; Alexander Koch; Nerea Ferreirós; Ana Mirceska; Pia Zeiner; Michel Mittelbronn; Amin Derouiche; Helmuth Steinmetz; Christian Foerch; Josef Pfeilschifter; Waltraud Pfeilschifter

doi:10.1371/journal.pone.0070124

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Open Access

Peer-reviewed

Research Article

FTY720 Treatment in the Convalescence Period Improves Functional Recovery and Reduces Reactive Astrogliosis in Photothrombotic Stroke

Robert Brunkhorst ,

* E-mail: robert.brunkhorst@kgu.de

Affiliations Department of Neurology, Goethe University Hospital, Frankfurt am Main, Germany, Department of General Pharmacology and Toxicology, Goethe University Hospital, Frankfurt am Main, Germany
⨯
Nathalie Kanaan,

Affiliations Department of Neurology, Goethe University Hospital, Frankfurt am Main, Germany, Department of General Pharmacology and Toxicology, Goethe University Hospital, Frankfurt am Main, Germany
⨯
Alexander Koch,

Affiliation Department of General Pharmacology and Toxicology, Goethe University Hospital, Frankfurt am Main, Germany
⨯
Nerea Ferreirós,

Affiliation Department of Clinical Pharmacology, Goethe University Hospital, Frankfurt am Main, Germany
⨯
Ana Mirceska,

Affiliation Department of General Pharmacology and Toxicology, Goethe University Hospital, Frankfurt am Main, Germany
⨯
Pia Zeiner,

Affiliations Department of Neurology, Goethe University Hospital, Frankfurt am Main, Germany, Department of Neuropathology, Goethe University Hospital, Frankfurt am Main, Germany
⨯
Michel Mittelbronn,

Affiliation Department of Neuropathology, Goethe University Hospital, Frankfurt am Main, Germany
⨯
Amin Derouiche,

Affiliation Department of Anatomy II, Goethe University Hospital, Frankfurt am Main, Germany
⨯
Helmuth Steinmetz,

Affiliation Department of Neurology, Goethe University Hospital, Frankfurt am Main, Germany
⨯
Christian Foerch,

Affiliation Department of Neurology, Goethe University Hospital, Frankfurt am Main, Germany
⨯
Josef Pfeilschifter,

Affiliation Department of General Pharmacology and Toxicology, Goethe University Hospital, Frankfurt am Main, Germany
⨯
Waltraud Pfeilschifter

Affiliations Department of Neurology, Goethe University Hospital, Frankfurt am Main, Germany, Department of General Pharmacology and Toxicology, Goethe University Hospital, Frankfurt am Main, Germany
⨯

FTY720 Treatment in the Convalescence Period Improves Functional Recovery and Reduces Reactive Astrogliosis in Photothrombotic Stroke

Robert Brunkhorst,
Nathalie Kanaan,
Alexander Koch,
Nerea Ferreirós,
Ana Mirceska,
Pia Zeiner,
Michel Mittelbronn,
Amin Derouiche,
Helmuth Steinmetz,
Christian Foerch

Published: July 31, 2013
https://doi.org/10.1371/journal.pone.0070124

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