Involvement of the Clock Gene Rev-erb alpha in the Regulation of Glucagon Secretion in Pancreatic Alpha-Cells

Elaine Vieira; Laura Marroquí; Ana Lucia C. Figueroa; Beatriz Merino; Rebeca Fernandez-Ruiz; Angel Nadal; Thomas P. Burris; Ramon Gomis; Ivan Quesada

doi:10.1371/journal.pone.0069939

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Peer-reviewed

Research Article

Involvement of the Clock Gene Rev-erb alpha in the Regulation of Glucagon Secretion in Pancreatic Alpha-Cells

Elaine Vieira ,

* E-mail: evieira@ciberdem.org (EV); ivanq@umh.es (IQ)

Affiliations Instituto de Bioingeniería, Universidad Miguel Hernandez de Elche, Elche, Spain, CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Barcelona, Spain
⨯
Laura Marroquí,

Affiliations Instituto de Bioingeniería, Universidad Miguel Hernandez de Elche, Elche, Spain, CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Barcelona, Spain
⨯
Ana Lucia C. Figueroa,

Affiliation Diabetes and Obesity Laboratory, Institut d'investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain
⨯
Beatriz Merino,

Affiliations Instituto de Bioingeniería, Universidad Miguel Hernandez de Elche, Elche, Spain, CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Barcelona, Spain
⨯
Rebeca Fernandez-Ruiz,

Affiliations CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Barcelona, Spain, Diabetes and Obesity Laboratory, Institut d'investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain
⨯
Angel Nadal,

Affiliations Instituto de Bioingeniería, Universidad Miguel Hernandez de Elche, Elche, Spain, CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Barcelona, Spain
⨯
Thomas P. Burris,

Affiliation Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida, United States of America
⨯
Ramon Gomis,

Affiliations CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Barcelona, Spain, Diabetes and Obesity Laboratory, Institut d'investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain, Endocrinology and Diabetes Unit, Hospital Clinic, Universitat de Barcelona, Barcelona, Spain
⨯
Ivan Quesada

* E-mail: evieira@ciberdem.org (EV); ivanq@umh.es (IQ)

Affiliations Instituto de Bioingeniería, Universidad Miguel Hernandez de Elche, Elche, Spain, CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Barcelona, Spain
⨯

Involvement of the Clock Gene Rev-erb alpha in the Regulation of Glucagon Secretion in Pancreatic Alpha-Cells

Elaine Vieira,
Laura Marroquí,
Ana Lucia C. Figueroa,
Beatriz Merino,
Rebeca Fernandez-Ruiz,
Angel Nadal,
Thomas P. Burris,
Ramon Gomis,
Ivan Quesada

Published: July 25, 2013
https://doi.org/10.1371/journal.pone.0069939

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Glucose
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Glucagon
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Secretion
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Gene expression
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Gene regulation
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Small interfering RNA
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