Histone Deacetylase Inhibition Enhances Self Renewal and Cardioprotection by Human Cord Blood-Derived CD34+ Cells

Ilaria Burba; Gualtiero I. Colombo; Lidia Irene Staszewsky; Marco De Simone; Paolo Devanna; Simona Nanni; Daniele Avitabile; Fabiola Molla; Simona Cosentino; Ilaria Russo; Noeleen De Angelis; Annarita Soldo; Antonella Biondi; Elisa Gambini; Carlo Gaetano; Antonella Farsetti; Giulio Pompilio; Roberto Latini; Maurizio C. Capogrossi; Maurizio Pesce

doi:10.1371/journal.pone.0022158

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Research Article

Histone Deacetylase Inhibition Enhances Self Renewal and Cardioprotection by Human Cord Blood-Derived CD34⁺ Cells

Ilaria Burba,

Affiliation Laboratorio di Biologia Vascolare e Medicina Rigenerativa, Centro Cardiologico Monzino, IRCCS, Milan, Italy
⨯
Gualtiero I. Colombo,

Affiliation Laboratorio di Genomica Funzionale ed Immunologia, Centro Cardiologico Monzino, IRCCS, Milan, Italy
⨯
Lidia Irene Staszewsky,

Affiliation Dipartimento di Scienze Cardiovascolari, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
⨯
Marco De Simone,

Affiliation Laboratorio di Biologia Vascolare e Medicina Rigenerativa, Centro Cardiologico Monzino, IRCCS, Milan, Italy
⨯
Paolo Devanna,

Affiliation Laboratorio di Biologia Vascolare e Medicina Rigenerativa, Centro Cardiologico Monzino, IRCCS, Milan, Italy
⨯
Simona Nanni,

Affiliation Istituto di Patologia Medica, Università Cattolica del Sacro Cuore, Rome, Italy
⨯
Daniele Avitabile,

Affiliation Laboratorio di Biologia Vascolare e Medicina Rigenerativa, Centro Cardiologico Monzino, IRCCS, Milan, Italy
⨯
Fabiola Molla,

Affiliation Dipartimento di Scienze Cardiovascolari, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
⨯
Simona Cosentino,

Affiliation Laboratorio di Aterotrombosi, Centro Cardiologico Monzino, IRCCS, Milan, Italy
⨯
Ilaria Russo,

Affiliation Dipartimento di Scienze Cardiovascolari, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
⨯
Noeleen De Angelis,

Affiliation Dipartimento di Scienze Cardiovascolari, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
⨯
Annarita Soldo,

Affiliation Dipartimento di Scienze Cardiovascolari, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
⨯
Antonella Biondi,

Affiliation Dipartimento di Scienze Cardiovascolari, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
⨯
Elisa Gambini,

Affiliation Laboratorio di Biologia Vascolare e Medicina Rigenerativa, Centro Cardiologico Monzino, IRCCS, Milan, Italy
⨯
Carlo Gaetano,

Affiliation Laboratorio di Patologia Vascolare, Istituto Dermopatico dell' Immacolata, IDI-IRCCS, Rome, Italy
⨯
Antonella Farsetti,

Affiliation Dipartimento di Oncologia Sperimentale, Istituto Regina Elena, Rome, Italy
⨯
Giulio Pompilio,

Affiliation Laboratorio di Biologia Vascolare e Medicina Rigenerativa, Centro Cardiologico Monzino, IRCCS, Milan, Italy
⨯
Roberto Latini,

Affiliation Dipartimento di Scienze Cardiovascolari, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
⨯
Maurizio C. Capogrossi,

Affiliation Laboratorio di Patologia Vascolare, Istituto Dermopatico dell' Immacolata, IDI-IRCCS, Rome, Italy
⨯
[ ... ],
Maurizio Pesce

* E-mail: maurizio.pesce@ccfm.it

Affiliation Laboratorio di Biologia Vascolare e Medicina Rigenerativa, Centro Cardiologico Monzino, IRCCS, Milan, Italy
⨯
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Histone Deacetylase Inhibition Enhances Self Renewal and Cardioprotection by Human Cord Blood-Derived CD34⁺ Cells

Ilaria Burba,
Gualtiero I. Colombo,
Lidia Irene Staszewsky,
Marco De Simone,
Paolo Devanna,
Simona Nanni,
Daniele Avitabile,
Fabiola Molla,
Simona Cosentino,
Ilaria Russo

Published: July 18, 2011
https://doi.org/10.1371/journal.pone.0022158

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