Fucosylated but Not Sialylated Milk Oligosaccharides Diminish Colon Motor Contractions

John Bienenstock; Rachael H. Buck; Hawley Linke; Paul Forsythe; Andrew M. Stanisz; Wolfgang A. Kunze

doi:10.1371/journal.pone.0076236

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Peer-reviewed

Research Article

Fucosylated but Not Sialylated Milk Oligosaccharides Diminish Colon Motor Contractions

John Bienenstock ,

* E-mail: bienens@mcmaster.ca

Affiliations McMaster Brain-Body Institute at St Joseph’s Healthcare, Hamilton, Ontario, Canada, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
⨯
Rachael H. Buck,

Affiliation Abbott Nutrition, a Division of Abbott Laboratories, Columbus, Ohio, United States of America
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Hawley Linke,

Affiliation Abbott Nutrition, a Division of Abbott Laboratories, Columbus, Ohio, United States of America
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Paul Forsythe,

Affiliations Department of Medicine, McMaster University, Hamilton, Ontario, Canada, Firestone Institute for Respiratory Health, Hamilton, Ontario, Canada
⨯
Andrew M. Stanisz,

Affiliation McMaster Brain-Body Institute at St Joseph’s Healthcare, Hamilton, Ontario, Canada
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Wolfgang A. Kunze

Affiliations McMaster Brain-Body Institute at St Joseph’s Healthcare, Hamilton, Ontario, Canada, Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada, Farncombe Family Digestive Health Institute, Hamilton, Ontario, Canada
⨯

Fucosylated but Not Sialylated Milk Oligosaccharides Diminish Colon Motor Contractions

John Bienenstock,
Rachael H. Buck,
Hawley Linke,
Paul Forsythe,
Andrew M. Stanisz,
Wolfgang A. Kunze

Published: October 2, 2013
https://doi.org/10.1371/journal.pone.0076236

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3’FL or 3FL?

Posted by wmu249 on 16 Mar 2022 at 15:01 GMT

1. The word "fucosylactose" should be "fucosyllactose".
2. All the text showed that one of the research subjects is 3’FL (3’-fucosyllactose). Authors mentioned that it is chemically synthesized and did not give the citation about it. May I ask that it is 3’FL or 3FL. 3’FL and 3FL are totally different compounds. 3FL is an abundant HMO, but 3’FL is not. The authors showed that 3’FL is a normal constituent of mouse milk, based on the citation [27]. However, the citation 27 actually mentioned 3FL, but not 3’FL.

No competing interests declared.

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Fucosylated but Not Sialylated Milk Oligosaccharides Diminish Colon Motor Contractions

Fucosylated but Not Sialylated Milk Oligosaccharides Diminish Colon Motor Contractions

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3’FL or 3FL?

Posted by wmu249 on 16 Mar 2022 at 15:01 GMT