Urinary α 1-microglobulin and β 2-microglobulin as markers of early kidney injury in HIV-positive male patients on tenofovir-based antiretroviral therapy

Xiao Li Yu; Wen Sun; Li Liu; Ke Hong; Hui Song

doi:10.1371/journal.pone.0303442

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Open Access

Peer-reviewed

Research Article

Urinary α 1-microglobulin and β 2-microglobulin as markers of early kidney injury in HIV-positive male patients on tenofovir-based antiretroviral therapy

Xiao Li Yu,

Roles Conceptualization, Investigation

Affiliations The Fourth Department of Infectious Diseases, Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China, Hubei Clinical Research Center for Infectious Diseases, Wuhan, China, Wuhan Research Center for Communicable Disease Diagnosis and Treatment, Chinese Academy of Medical Sciences, Wuhan, China, Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology and Wuhan Jinyintan Hospital, Chinese Academy of Sciences, Wuhan, China
⨯
Wen Sun,

Roles Investigation

Affiliations The Fourth Department of Infectious Diseases, Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China, Hubei Clinical Research Center for Infectious Diseases, Wuhan, China, Wuhan Research Center for Communicable Disease Diagnosis and Treatment, Chinese Academy of Medical Sciences, Wuhan, China, Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology and Wuhan Jinyintan Hospital, Chinese Academy of Sciences, Wuhan, China
⨯
Li Liu,

Roles Investigation

Affiliations The Fourth Department of Infectious Diseases, Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China, Hubei Clinical Research Center for Infectious Diseases, Wuhan, China, Wuhan Research Center for Communicable Disease Diagnosis and Treatment, Chinese Academy of Medical Sciences, Wuhan, China, Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology and Wuhan Jinyintan Hospital, Chinese Academy of Sciences, Wuhan, China
⨯
Ke Hong ,

Contributed equally to this work with: Ke Hong, Hui Song

Roles Conceptualization, Writing – original draft

* E-mail: 1864200020@e.gzhu.edu.cn

Affiliations The Fourth Department of Infectious Diseases, Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China, Hubei Clinical Research Center for Infectious Diseases, Wuhan, China, Wuhan Research Center for Communicable Disease Diagnosis and Treatment, Chinese Academy of Medical Sciences, Wuhan, China, Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology and Wuhan Jinyintan Hospital, Chinese Academy of Sciences, Wuhan, China

https://orcid.org/0000-0002-9708-9982

⨯
Hui Song

Contributed equally to this work with: Ke Hong, Hui Song

Roles Methodology, Writing – review & editing

Affiliations The Fourth Department of Infectious Diseases, Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China, Hubei Clinical Research Center for Infectious Diseases, Wuhan, China, Wuhan Research Center for Communicable Disease Diagnosis and Treatment, Chinese Academy of Medical Sciences, Wuhan, China, Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology and Wuhan Jinyintan Hospital, Chinese Academy of Sciences, Wuhan, China
⨯

Urinary α 1-microglobulin and β 2-microglobulin as markers of early kidney injury in HIV-positive male patients on tenofovir-based antiretroviral therapy

Xiao Li Yu,
Wen Sun,
Li Liu,
Ke Hong,
Hui Song

Published: June 17, 2024
https://doi.org/10.1371/journal.pone.0303442

About the Authors

Xiao Li Yu

Roles Conceptualization, Investigation

Affiliations The Fourth Department of Infectious Diseases, Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China, Hubei Clinical Research Center for Infectious Diseases, Wuhan, China, Wuhan Research Center for Communicable Disease Diagnosis and Treatment, Chinese Academy of Medical Sciences, Wuhan, China, Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology and Wuhan Jinyintan Hospital, Chinese Academy of Sciences, Wuhan, China

Wen Sun

Roles Investigation

Li Liu

Roles Investigation

Ke Hong

Contributed equally to this work with: Ke Hong, Hui Song

Roles Conceptualization, Writing – original draft

* E-mail: 1864200020@e.gzhu.edu.cn

https://orcid.org/0000-0002-9708-9982

Hui Song

Contributed equally to this work with: Ke Hong, Hui Song

Roles Methodology, Writing – review & editing

Competing Interests

The authors have declared that no competing interests exist.

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HIV
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HIV diagnosis and management
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Renal system
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Antiretroviral therapy
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Urine
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Antiviral therapy
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Kidneys
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Renal analysis
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