About the Authors

Masako Takashima

masako@jcm.riken.jp

Affiliation Japan Collection of Microorganisms, RIKEN BioResource Center, Koyadai, Tsukuba, Ibaraki, 305–0074, Japan

Ri-ichiroh Manabe

Affiliation Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Suehiro-cho, Tsurumiku, Yokohama, Kanagawa, 230–0045, Japan

Wataru Iwasaki

Affiliation Department of Biological Sciences, Graduate School of Science, the University of Tokyo, Yayoi, Bunkyoku, Tokyo, 113–0032, Japan

Akira Ohyama

Affiliation Planning, in silico biology, inc., SOHO Station 706, 24–8 Yamashita-cho, Naka-ku, Yokohama, Kanagawa, 231–0023 Japan

Moriya Ohkuma

Affiliation Japan Collection of Microorganisms, RIKEN BioResource Center, Koyadai, Tsukuba, Ibaraki, 305–0074, Japan

Takashi Sugita

Affiliation Department of Microbiology, Meiji Pharmaceutical University, Kiyose, Tokyo, 204–8588, Japan

Competing Interests

Akira Ohyama is the CEO of In silico biology, inc. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: MT RM MO TS. Performed the experiments: MT RM TS. Analyzed the data: MT RM WI AO TS. Wrote the paper: MT RM WI AO MO TS.