About the Authors

Rebekah W. Moehring

rebekah.moehring@duke.edu

Affiliations Department of Medicine, Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Medicine, Division of Infectious Diseases, Durham Veterans Affairs Medical Center, Durham, North Carolina, United States of America

Richard Sloane

Affiliation Division of Geriatrics, Duke University Medical Center, Durham, North Carolina, United States of America

Luke F. Chen

Affiliation Department of Medicine, Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, United States of America

Emily C. Smathers

Affiliation Department of Medicine, Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, United States of America

Kenneth E. Schmader

Affiliations Division of Geriatrics, Duke University Medical Center, Durham, North Carolina, United States of America, Geriatric Research Education and Clinical Center, Durham Veterans Affairs Medical Center, Durham, North Carolina, United States of America

Vance G. Fowler Jr.

Affiliation Department of Medicine, Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, United States of America

David J. Weber

Affiliation Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Daniel J. Sexton

Affiliation Department of Medicine, Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, United States of America

Deverick J. Anderson

Affiliation Department of Medicine, Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, United States of America

Competing Interests

The authors have read the journal’s policy and have the following conflicts: Rebekah W. Moehring – RWM has no direct conflicts. RWM has received royalties from UpToDate, Inc. Richard Sloane - None. Luke F. Chen – LFC has no direct conflicts. LFC received grant support from Merck and Optimer Pharmaceuticals, and is on the speaker’s bureau for Cubist and Optimer. Emily C. Smathers - None. Kenneth E. Schmader – KES has no direct conflicts, he has received grant support from Merck. Vance G. Fowler Jr. - VGF has no direct conflicts. He was chair of Merck V710 Scientific Advisory Committee, has received grant support from Merck, Cerexa, Pfizer, Novartis, Advanced Liquid Logics, MedImmune, and the National Institutes of Health, has been a paid consultant for Merck, Astellas, Affinium, Theravance, Cubist, Cerexa, Durata, Pfizer, NovaDigm, Novartis, Medicines Company, Biosynexus, MedImmune, Galderma, and Inimex, and has received honoraria from Merck, Astellas, Cubist, Pfizer, Theravance, and Novartis. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RWM DJA DJS KES. Performed the experiments: RWM RS ECS DJA. Analyzed the data: RWM RS DJA. Contributed reagents/materials/analysis tools: RWM RS DJA. Wrote the manuscript: RWM DJA DJS DJW. Provided critical review and edits of the manuscript: LFC VGF DJW KES.