Quantitative modeling of signaling in aggressive B cell lymphoma unveils conserved core network

• Bertram Klinger ,

  Contributed equally to this work with: Bertram Klinger, Isabel Rausch, Nils Blüthgen, Dieter Kube

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: bertram.klinger@charite.de (BK); nils.bluethgen@charite.de (NB); Dieter.Kube@med.uni-goettingen.de (DK)

  Affiliations Institute of Pathology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, Institute for Theoretical Biology, Humboldt-Universität zu Berlin, Berlin, Germany, German Cancer Consortium (DKTK) Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany

  https://orcid.org/0000-0003-0242-1506

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• Isabel Rausch ,

  Contributed equally to this work with: Bertram Klinger, Isabel Rausch, Nils Blüthgen, Dieter Kube

  Roles Conceptualization, Data curation, Investigation, Visualization

  Affiliations Clinic of Hematology and Medical Oncology, University Medical Centre Goettingen, Göttingen, Germany, ZytoVision GmbH, Bremerhaven, Germany

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• Anja Sieber,

  Roles Data curation, Investigation

  Affiliation Institute of Pathology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

  https://orcid.org/0000-0001-6588-8547

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• Helmut Kutz,

  Roles Investigation

  Affiliation Research Unit Gene Vectors, Helmholtz Center Munich—German Research Center for Environmental Health, Munich, Germany

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• Vanessa Kruse,

  Roles Investigation

  Affiliation Clinic of Hematology and Medical Oncology, University Medical Centre Goettingen, Göttingen, Germany

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• Marieluise Kirchner,

  Roles Data curation, Investigation

  Affiliation Core Unit Proteomics, Berlin Institute of Health at Charité—Universitaetsmedizin Berlin and Max-Delbrueck-Center for Molecular Medicine, Berlin, Germany

  https://orcid.org/0000-0002-7049-534X

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• Philipp Mertins,

  Roles Resources, Supervision

  Affiliation Core Unit Proteomics, Berlin Institute of Health at Charité—Universitaetsmedizin Berlin and Max-Delbrueck-Center for Molecular Medicine, Berlin, Germany

  https://orcid.org/0000-0002-2245-528X

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• Arnd Kieser,

  Roles Conceptualization, Funding acquisition, Investigation, Resources, Supervision, Writing – original draft

  Affiliations Research Unit Gene Vectors, Helmholtz Center Munich—German Research Center for Environmental Health, Munich, Germany, Research Unit Signaling and Translation, Helmholtz Center Munich—German Research Center for Environmental Health, Neuherberg, Germany, German Center for Infection Research (DZIF), Partner Site Munich, Germany

  https://orcid.org/0000-0003-0783-1950

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• Nils Blüthgen ,

  Contributed equally to this work with: Bertram Klinger, Isabel Rausch, Nils Blüthgen, Dieter Kube

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: bertram.klinger@charite.de (BK); nils.bluethgen@charite.de (NB); Dieter.Kube@med.uni-goettingen.de (DK)

  Affiliations Institute of Pathology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, Institute for Theoretical Biology, Humboldt-Universität zu Berlin, Berlin, Germany, German Cancer Consortium (DKTK) Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany

  https://orcid.org/0000-0002-0171-7447

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• Dieter Kube

  Contributed equally to this work with: Bertram Klinger, Isabel Rausch, Nils Blüthgen, Dieter Kube

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: bertram.klinger@charite.de (BK); nils.bluethgen@charite.de (NB); Dieter.Kube@med.uni-goettingen.de (DK)

  Affiliation Clinic of Hematology and Medical Oncology, University Medical Centre Goettingen, Göttingen, Germany

  https://orcid.org/0000-0001-7760-525X

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