Improved prediction of smoking status via isoform-aware RNA-seq deep learning models

• Zifeng Wang,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft

  Affiliation Department of ECE, Northeastern University, Boston, Massachusetts, United States

  https://orcid.org/0000-0002-0068-9042

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• Aria Masoomi,

  Roles Methodology, Writing – review & editing

  Affiliation Department of ECE, Northeastern University, Boston, Massachusetts, United States

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• Zhonghui Xu,

  Roles Data curation, Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliation Channing Division of Network Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States

  https://orcid.org/0000-0002-6469-9178

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• Adel Boueiz,

  Roles Writing – review & editing

  Affiliations Channing Division of Network Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States, Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States

  https://orcid.org/0000-0003-1638-8575

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• Sool Lee,

  Roles Writing – review & editing

  Affiliation Channing Division of Network Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States

  https://orcid.org/0000-0002-6730-0062

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• Tingting Zhao,

  Roles Writing – review & editing

  Affiliation Department of ECE, Northeastern University, Boston, Massachusetts, United States

  https://orcid.org/0000-0001-6418-699X

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• Russell Bowler,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliation Division of Pulmonary and Critical Care Medicine, National Jewish Health, Denver, Colorado, United States

  https://orcid.org/0000-0003-4651-363X

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• Michael Cho,

  Roles Writing – review & editing

  Affiliations Channing Division of Network Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States, Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States

  https://orcid.org/0000-0002-4907-1657

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• Edwin K. Silverman,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliations Channing Division of Network Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States, Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States

  https://orcid.org/0000-0002-3641-3822

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• Craig Hersh,

  Roles Writing – review & editing

  Affiliations Channing Division of Network Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States, Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States

  https://orcid.org/0000-0002-1342-4334

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• Jennifer Dy,

  Roles Conceptualization, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliation Department of ECE, Northeastern University, Boston, Massachusetts, United States

  https://orcid.org/0000-0002-8430-134X

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• Peter J. Castaldi

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: repjc@channing.harvard.edu

  Affiliations Channing Division of Network Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States, Division of General Internal Medicine and Primary Care, Brigham and Women’s Hospital, Boston, Massachusetts, United States

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