About the Authors

Adam Skinner

Roles Conceptualization, Formal analysis, Writing – original draft

adam.skinner@sydney.edu.au

Affiliation Brain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia,

Eloisa Perez-Bennetts

Roles Conceptualization, Writing – review & editing

Affiliation Brain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia,

Frank Iorfino

Roles Conceptualization, Writing – review & editing

Affiliation Brain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia,

Mathew Varidel

Roles Conceptualization, Writing – review & editing

Affiliation Brain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia,

Matthew Richards

Roles Conceptualization, Writing – review & editing

Affiliation Brain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia,

Jo-An Occhipinti

Roles Conceptualization, Writing – review & editing

Affiliations Brain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia,, Computer Simulation and Advanced Research Technologies (CSART), Sydney, Australia

Yun Ju Christine Song

Roles Conceptualization, Writing – review & editing

Affiliation Brain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia,

Sebastian Rosenberg

Roles Conceptualization, Writing – review & editing

Affiliation Brain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia,

Elizabeth M. Scott

Roles Conceptualization, Writing – review & editing

Affiliation Brain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia,

Ian B. Hickie

Roles Conceptualization, Writing – review & editing

Affiliation Brain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia,

Competing Interests

The authors have read the journal’s policy and have the following competing interests: J-AO is Head of Systems Modelling, Simulation & Data Science at the Brain and Mind Centre, University of Sydney and Managing Director of Computer Simulation and Advanced Research Technologies (CSART). EMS is the medical director of the Young Adult Mental Health Unit at St Vincent’s Hospital in Darlinghurst, the Adult Mental Health discipline leader in the University of Notre Dame School of Medicine, a research affiliate at the University of Sydney, and a consultant psychiatrist. EMS has received honoraria for educational seminars related to the clinical management of depressive disorders supported by Servier and Eli-Lilly, participated in a national advisory board for the antidepressant compound Pristiq (Pfizer), and was the national coordinator of an antidepressant trial sponsored by Servier, outside of the submitted work. IBH was an inaugural Commissioner on Australia’s National Mental Health Commission (2012–18). IBH is the Co-Director, Health and Policy at the Brain and Mind Centre, University of Sydney. The Brain and Mind Centre operates an early-intervention youth service at Camperdown under contract to headspace. IBH has previously led community-based and pharmaceutical industry-supported (Wyeth, Eli Lily, Servier, Pfizer, AstraZeneca) projects focused on the identification and better management of anxiety and depression, outside of the submitted work. IBH was a member of the Medical Advisory Panel for Medibank Private until October 2017, a Board Member of Psychosis Australia Trust, and a member of Veterans Mental Health Clinical Reference group. IBH is the Chief Scientific Advisor to, and a 3.2% equity shareholder in, InnoWell Pty Ltd. InnoWell was formed by the University of Sydney (45% equity) and PwC (Australia; 45% equity) to deliver the $30 M Australian Government-funded Project Synergy (2017–20; a three-year program for the transformation of mental health services) and to lead transformation of mental health services internationally through the use of innovative technologies, outside of the submitted work. There are no patents, products in development or marketed products associated with this research to declare. This does not alter our adherence to PLOS policies on sharing data and materials.